Understanding your Immune System

The immune system is a complex network of cells, tissues, and organs that work together to defend the body against harmful pathogens, such as bacteria, viruses, and parasites. It plays a crucial role in maintaining the body's overall health and well-being. The immune system consists of two primary components: the innate immune system and the adaptive immune system.
The innate immune system is the first line of defense and provides immediate, non-specific protection. It includes physical barriers like the skin and mucous membranes, as well as various immune cells such as neutrophils and macrophages. These cells detect and eliminate pathogens through mechanisms like phagocytosis and inflammation.
The adaptive immune system, on the other hand, provides a more targeted and specific defense against pathogens. It involves the activation of specialized cells, known as lymphocytes, which include B cells and T cells. Among the T cells, two crucial subsets called T helper 1 (Th1) and T helper 2 (Th2) cells play a significant crucial roles in the immune system. Th1 cells are involved in cellular immunity and defense against intracellular pathogens, while Th2 cells are associated with humoral immunity and defense against extracellular pathogens. An imbalance between Th1 and Th2 activity can contribute to various immune-related disorders.

In turn, your adaptive immune system is divided into T cells and B cells.

T Cells
Control and regulate our immune response
CD4 Helper Cells

T helper 1 (Th1) cells: releases IL2 & γ-IFN cytokines

T helper 2 (Th2) cells: releases IL4, IL5, IL6 & IL10 & TNF cytokines

T regulatory cells (Treg) cells: inhibit Th1 & Th2 responses

CD8 Cytotoxic Cells
Guided missiles of the immune cells killing viruses & malignant cells
B Cells
Synthesise and release antibodies which recognize and destroy invading pathogens before they cause disease

How Prepared Immune™ works to maintain T-cell balance

Plant sterols and sterolins, also known as phytosterols and phytosterolins, are naturally occurring compounds found in plants. They have been studied for their potential effects on immune function, including their ability to modulate Th1 and Th2 cell activity. Plant sterols and sterolins can influence the production of cytokines, which are small signaling molecules involved in immune cell communication. They may increase the production of Th1-associated cytokines (e.g., interferon-gamma) and decrease Th2-associated cytokines (e.g., interleukin-4). This shift can help rebalance Th1 and Th2 activity.
Grape seed extract is a natural supplement that is rich in antioxidants, primarily flavonoids and oligomeric proanthocyanidins. studies suggest that grape seed extract may affect the production and release of certain cytokines involved in Th1 and Th2 cell responses. It has been observed to down-regulate the expression of Th2-associated cytokines, such as interleukin-4 (IL-4), and up-regulate Th1 associated cytokines, such as interferon-gamma (γ-IFN). This modulation can contribute to a balanced Th1/Th2 immune response.
Overactive Immune System Symptoms
  • Heightened seasonal sensitivity to dust, pollen and mold
  • Digestive issues
  • Fatigue
  • Sinus issues
  • Joint and muscle issues
  • Skin issues
  • Hair loss
Underactive Immune System Symptoms
  • Fatigue from inability to fight off threats
  • Frequently not feeling well
  • Increase susceptibility to invading threats
  • Plant Sterols and Sterolins

    In nature, plants contain plant fats called sterols (beta sitosterol/BSS), and attached to them are their glucoside sterolins (beta sitosterol glucoside/BSSG). These plant sterols & sterolins in a specific 100:1 ratio have been shown to:

    Activate Treg Cells, balancing Th1 & Th2 cells which control & regulate our immune system

    Reduce inflammatory responses Reduce our cortisol stress response
  • Grape Seed Extract

    Grape seed extract, rich in proanthocyaninidins, is a powerful antioxidant and anti-inflammatory agent which has been shown to:

    Modulate the immune system by also balancing the Th1 & Th2 cells

    Reduces inflammatory responses Increases blood flow, oxygen and nutrient delivery to muscles Increases levels of beneficial bacteria in the gut
Triple Immune Support*
Triple Active Inflammatory Response*
  • 1

    Boosts the immune system*

  • 2

    Balances the immune system*

  • 3

    Reduces inflammatory responses*

  • 1

    Reduces oxidative stress and inflammatory reactions at their root

  • 2

    Inhibits the production of molecules which promote inflammation

  • 3

    Balances immune cell function for a balanced immune response

What makes Prepared Immune™ different?

Most immune supplements are designed to only boost your immune system, but what if your immune system doesn’t need a boost?
What if your immune sytem is imbalanced and is instead overactive and needs to be regulated down?
Prepared Immune™ brings back immune system balance and control, as it thinks for you to boost your immune system when it needs a boost, and balance your immune system when it needs to be regulated down.
  • Each capsule contains:

    Proanthocyanadins (from grape seed extract) 70 mg
    Sterols (from pine phytosterols) 30 mg
    Sterolins 300 mcg

    Free from sugar, lactose, soy, preservatives

  • Vegetarian Friendly

    Lactose Free

    Sugar Free


    Adults and children over 12 years old: One capsule in the morning and one capsule at night
    Children over 5 years old: One capsule daily

Rethink Immunity

Backed by Science since 1996, patent pending on the formulation, & Informed Sport Approval, Prepared Immune is the Insurance Policy for your immune system.
1. P.R. Donald; J.H. Lamprecht; M. Freestone; C.F.Albrecht; P.J.D. Bouic; D. Kotze; P.P. van Jaarsveld, A randomized placebo-controlled trial of the efficacy of beta-sitosterol and its glucoside as adjuvants in the treatment of pulmonary tuberculosis: International Journal of Tuberculosis and Lung Disease, vol. 1 (5), pp. 518-522, July 1997
2. R.R. Berges; J. Windeler; H.J. Trampisch; T.H. Senge and the b-sitosterol study group, Randomized, placebo-controlled, double-blind clinical trial of B-sitosterol in patients with benign prostatic hyperplasia: Lancet, vol. 345, no. 8964, pp. 1529-32, June 1995
3. P.J.D. Bouic; P.P. van Jaarsveld; A. Clark; J.H. Lamprecht; M. Freestone and R.W. Liebenberg, The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runner: Inhibition of post marathon immune suppression and inflammation; International Journal of Sports Medicine, vol. 234, no. 5636, pp.1221-31, May 1997.
4. Dreher, Henry: The Immune Power Personality, Penguin Books USA Inc., New York, 1995.
5. P.K.D Bouic; S.Etsebeth; R.W. Liebenberg et al, Beta-sitosterol and beta-sitosterol glucoside stimulate the human peripheral blood lymphocyte proliferation: Implications for their use as an immunomodulatory vitamin combination; Int. J. Immunopharmac, vol. 18, no. 12, pp. 693-700, 1996.
6. U. Breytenbach; A. Clark; J. Lamprecht; P Bouic, Flow Cytometric analysis of the TH1-TH2 balance in healthy individuals and patients infected with the human immunodeficiency virus (HIV) receiving a plant sterol/sterolin mixture; Cell Biology International, vol. 25, No.1, pp 43-49, 2001
7. N. Nair; S. Mahajan; R.Chawda et. Al, Grape seed extract activate TH1 cells in vitro; Clinical and Diagnostic Laboratory Immunology, p. 470-476, Mar. 2002
8. R. Nallathambi; A.Poulev; J.B Zuk et. al., Proanthocyanidin-Rich grape seed extract reduces inflammation and oxidative stress and restores tight junction barrier function in Caco-2 colon cells; Nutrients, 2020, 12, 1623; doi:10.3390/nu12061623
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.